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Essential Measures are only those items that are critical to the collection of the Measure or are necessary for the interpretation of results. Essential Measures are integral to the Measure. Without such information the data collected would be incomplete and/or misleading.
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Browse » Collections » Tobacco Regulatory Research » Tobacco Regulatory Research: Agent » Nicotine Content

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Measure: Nicotine Content   #730300

Definition: This measures the amount of nicotine in tobacco products including smokeless tobacco, tobacco filler, and electronic cigarette liquid contents or refill solutions (e-liquids).

Purpose: The purpose of this measure is to analyze the pH and the amount of nicotine in smokeless tobacco, tobacco filler, and electronic cigarette liquid contents or refill solutions (e-liquids). Nicotine in tobacco exists predominantly in two pH-dependent forms. Protonated nicotine is the predominant form in tobacco, but additives of tobacco can increase pH and convert a fraction of the nicotine into the non-protonated free-base form that is more bio-available and readily absorbed, contributing to higher addictiveness.


Keywords: Tobacco Regulatory Research, TRR, nicotine, nicotine content, pH, smokeless tobacco, cigarette, tobacco, cigarette filler tobacco, nicotine calculation, product characterization, tobacco laboratory management system, nicotine quantification, nicotine concentration, laboratory measurement, quality control, addiction

Measure Release Date: June 24, 2015

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