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Toolkit Guidance

The PhenX Toolkit expects Users to be responsible for following good scientific practices when conducting studies. This includes, but is not limited to, addressing human subject's issues and broad compliance with federal laws and regulations. Note that there can be inherent variability between studies even if the same protocols are used.

Certificate of Confidentiality:
NIH Genomic Data Sharing Policy:
A Code of Ethics for Public Health:
NHGRI informed consent resource:

The PhenX Toolkit provides high quality, standard measures for inclusion in a variety of studies. Because of the multifaceted Criteria for Evaluating Measures, PhenX measures are not "gold standards" per se. Toolkit Users need to be aware that some PhenX measures may not be appropriate for all study designs.

For general guidance with regard to study design, please see:

Please cite use of PhenX measures in your presentations and publications as:

Toolkit Users are encouraged to cite the source study for any measures/protocols they use.

The Toolkit recommends use of some proprietary protocols, and directs Users to the source of these protocols. Individual investigators are responsible for obtaining proprietary protocols and any associated licensing costs, and are responsible for complying with any license terms or other restrictions by the owners of those measures/protocols, including without limitation the owners’ requirements regarding the use of trademarks and trade names.

The PhenX Toolkit database and supporting documentation is released free of charge under the Creative Commons attribution license, the full terms of which can be found at PhenX Toolkit database downloads will be made available to the public following each major PhenX Toolkit release. The following attribution statement is provided for your use: "The Web-based PhenX Toolkit currently receives funding from the National Institutes of Health; official current and archived versions of the PhenX Toolkit are available at

PhenX is currently funded by the National Human Genome Research Institute (NHGRI), with co-funding provided by the National Institute on Drug Abuse (NIDA); Genomic Resource Grant Award Numbers: U01 U01 HG004597, 3U01 HG004597-02S1, and U41 HG007050.

How to cite use of PhenX measures:
Measures incorporated in this study were selected from the PhenX Toolkit version July 2, 2018, Ver 23. More »

How to cite the PhenX Toolkit:
Hamilton, et al. (2011) The PhenX Toolkit: Get the Most From Your Measures. American Journal of Epidemiology, 174(3), 253-60.

PhenX is funded by a Genomic Resource Grant, U41 HG007050, from NHGRI with co-funding from NIDA.

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